Vaccines should work, spread a concern: South African expert weighs in

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A leading virologist in South Africa, where the Omicron variant has surfaced, expects current vaccines will continue to cover those vaccinated against severe complaint and death from Covid-19. Jeffrey Dorfman, Associate Professor in Medical Virology at Stellenbosch University, bandied the variant and its counteraccusations
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. On sanguinity about vaccines

This is because the protection (from vaccines) seems to be intermediated by T cells, which can honor any part of the contagion, as opposed to neutralising antibody, which is concentrated upon the receptor list sphere, a part of the shaft protein. We don’t know a lot about the variant yet. There’s no direct’ substantiation of vulnerable escape — but that should come over the coming many weeks,” said Dorfman, who has been probing HIV and other contagious conditions.

Too many people have been infected with Omicron and linked as similar, he noted. “ Still, our former experience suggests that the vaccines will still help hospitalisation and death from Covid — but we do n’t know exactly how well. Also, case figures will go up briskly and higher if former infection with other variants doesn’t help infection with this new variant veritably well — and having further contagion around is more dangerous. We just do n’t know yet,” Dorfman said.

On advance infections

Advance infections in vaccinated individualities tend to be mild, but won’t always be so, especially in aged people, he said. “ We also see what seems like a youngish average age of people getting oppressively ill from Covid. A lot of that’s a result of targeting vaccination to aged people … As variants get further contagious, further people get infected, and the bones who get sick are the bones who weren’t infected lately and not vaccinated ( generally, not 100). We also get further children getting sick as they return to academy … I’m not apprehensive of any substantiation to suggest that what we see is further than these goods,” he said
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On mutations in combination

Dorfman appertained to the range of mutations in Omicron, numerous (but not each) of which have been seen before — and noway all together in the same variant. “ We’re concerned that protection, particularly protection from infection may be reduced. Also, it seems to be suitable to spread snappily, but the substantiation for that’s presently thin — there are about 70 or 80 cases detected in Gauteng fiefdom then in South Africa as of Wednesday last week,” he said.

On trip restrictions

Asked trip advisories issued by countries, he said “ Restrictions will dock spread, maybe for a short while. But it’s presumably formerly too late.”

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“ Estimates grounded upon the sequences we now hold suggest that Omicron came to be eventually betweenmid-September tomid-October, enough time to spread where there’s little surveillance. There’s also a worrying case of a woman who returned home to Belgium from Egypt with the variant. The other reports that I’ve seen are all linked to southern Africa … If it’s common enough in Egypt that a short- term rubberneck got it, also we should be upset,” he said.

He said there’s limited benefit to the detention that travel restrictions will give. “ In the case of Delta, some countries were starting to vaccinate, and keeping Delta out for a couple of months while vaccination rates went up might be counted as an important benefit. Now, many countries are in that position, and the public health benefit to a detention is more limited,” he said.

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